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Approved case-by-case

England regulates gene-edited plants under a new framework while the rest of the UK still follows restrictive European GMO rules.

Brexit has left the United Kingdom with a divided regulatory map for gene-edited crops. England has built a new approval system under the Genetic Technology (Precision Breeding) Act 2023 and the Genetic Technology (Precision Breeding) Regulations 2025. Scotland, Wales and Northern Ireland have not followed, and continue to regulate gene-edited plants under the older European Union-derived law that governs genetically modified organisms that have been heavily restricted since 2001. As of spring 2026 no precision-bred crop or animal has been authorized for sale as food or animal feed in England, and there is no immediate plan to do so.

The EU framework that the UK inherited was built during the political turbulence over GM crops in the 1990s and 2000s, and constructed around the precautionary principle: roughly, the idea that when a new technology might cause harm, the burden of proof falls on those introducing it rather than those opposing it. Politically, Brexit gave ministers room to depart from retained EU law. During its 2021 consultation response on genetic technologies, UK’s former farming minister George Eustice said that leaving the EU created an opportunity for a “more scientific and proportionate approach.” Economically, the government tied reform to food security, climate resilience, lower pesticide and fertilizer use, and the need to capitalize on Britain’s unusually strong research base in genetics, genomics, and agricultural science, tying reform to the country’s research strength at the John Innes Centre, Rothamsted Research, the James Hutton Institute and the National Institute of Agricultural Botany.

The shift began with the Genetic Technology (Precision Breeding) Act 2023 and became operational for plants under the Genetic Technology (Precision Breeding) Regulations 2025. As of spring 2026, no precision-bred crops or animals have yet been authorized for sale as food or animal feed anywhere in the UK. The change in English policy was driven by a combination of scientific, economic, and constitutional arguments. Under the 2023 Act, a plant qualifies as precision-bred under the new, lighter framework only if the genetic changes are stable and of a kind that could also have arisen through conventional agricultural methods: sexual crossing, spontaneous mutation, embryo rescue, grafting, induced mutation, and certain forms of cell fusion between sexually compatible plants. Any plant carrying DNA that is not present in the original species or in sexually compatible species, transgenic GMOs fall into this category, and remains subject to the older GMO rules. The English system is therefore not about technique, which still guides the process-based EU approach, but about the nature of the resulting change, the final product and not how it was created, like what is in place in the U.S. and Canada, though it still involves case-by-case oversight.

The UK Department for Environment, Food & Rural Affairs (Defra) oversees the new regulations. Companies seeking to release precision-bred plants for field trials or market them commercially must submit notices to Defra; Defra then publishes qualifying release and marketing notices on the public precision breeding register. Only precision-bred plants can be released or marketed under the English system. As of May 2026, the precision breeding register lists one marketing notice, for food trials for animal feed barley to lower methane release,  and four release notices: for camelina for increased seed size; garden pea for improved breeding; oilseed rape for enhanced erucic acid content in seed oil; and early flowering soybean.

On the agricultural side, outdoor field trials require a release notice to Defra. Commercial marketing requires a marketing notice and a formal precision-bred confirmation, issued after advice from ACRE, the Advisory Committee on Releases to the Environment. Defra publishes notices, ACRE’s advice and decisions on a public Precision Breeding Register. Food and feed safety then go through a separate process at the Food Standards Agency, which operates a two-tiered system. Tier 1 handles applications where the applicant’s own safety assessment identifies no concern, a process that is expected to take around two months. Tier 2 applies where a safety concern or material uncertainty has been identified and may take twelve to twenty-four months.

The other three nations in the UK are united in not adopting England’s route, but their positions are not identical. Scotland applies the EU law and has long stated its opposition to cultivating GM crops in the open environment. Wales similarly continues to classify these plants under the inherited European framework. Northern Ireland remains closely tied to the EU under post-Brexit arrangements and depends on the Northern Ireland Retail Movement Scheme.

The 2023 Act covers both plants and vertebrate animals, but the 2025 regulations implemented only the plant provisions. The public register covers plants only. The Nuffield Council on Bioethics noted in 2025 that animal regulations had not been introduced and that the government had indicated no immediate plans to do so. For now, that is where the line sits: gene-edited plants in England can enter the new approval process; gene-edited animals cannot.

 NGO Reaction

With the advent of gene editing, British environmental NGOs have recast their old anti-GMO “Frankenfoods” campaigns which had focused on the alleged dangers of foreign DNA. As CRISPR and other editing techniques do not require DNA from another species and having lost the approval battle, NGOs have abandoned those lines of attack and now focus on alleged unintended effects, labeling, traceability, and oversight.

 

The Sustainable Food Trust has argued that gene editing can produce unintended changes and that products developed with these techniques should remain under more restrictive GMO rules and called for a more restrictive framework. GeneWatch UK has for years opposed the food-and-feed framework for precision-bred products. GM Freeze, The Soil Association, and Organic Farmers & Growers have argued that the new rules would allow “unlabeled” and “untraceable” products, disrupting non-GE and organic markets, making it difficult and more costly for organic businesses to keep gene-edited material out of certified supply chains.

 

The strongest pushback has come through the courts. Beyond GM launched a legal challenge to the new regulations, arguing that Defra removed labeling, traceability, environmental review and information requirements for products the challengers still regard as genetically modified organisms. In making its case to the High Court, Beyond GM framed the dispute as one about “hidden GMOs.” The challenge has been echoed by Sustain and GMWatch, while Leigh Day’s 2025 announcement and its later notice that the High Court will hear the case show that opposition has moved beyond campaigning into active litigation.

 

RSPCA and Compassion in World Farming any future move to authorize gene-edited animals, although none is in the pipeline and ministers have given no indication of whether or when they might authorize them.  RSPCA has maintained for years that the bill is a “backward step” for animal welfare and public trust. Compassion in World Farming has argued that gene editing could perpetuate animal suffering by adapting animals to factory-farming systems instead of changing those systems and has urged ministers to exclude uses that would merely sustain those systems. More recently, in a parliamentary briefing, the Nuffield Council on Bioethics said ministers should not move ahead on farmed animals without clear public benefit, strong welfare safeguards, and public legitimacy, and that higher productivity on its own would not justify the use of genome editing in farmed animals.

With the advent of gene editing, British environmental NGOs have recast earlier campaigns that focused on foreign DNA. Because techniques such as CRISPR do not necessarily involve inserting DNA from another species, criticism has shifted toward unintended effects, labelling, traceability and oversight. The Sustainable Food Trust argues that precision-bred products risk entering the food system without the safeguards traditionally applied to genetically modified organisms, and has. GeneWatch UK argues the precision breeding regime removes key safeguards, especially traceability, validated detection methods, and routine environmental risk assessment, and warns this creates oversight and trade risks.

The organic and non-GMO sector has focused mostly on control. That criticism is most developed in the organic and non-GM sector. GM Freeze has campaigned for mandatory labelling of genetically engineered seeds, arguing that the absence of labelling undermines transparency and choice, while its response to the regulations being passed without a whisper frames the new regime as a significant deregulatory step introduced with limited public scrutiny. The Soil Association argues that weaker traceability rules will make it harder and more costly for organic farmers and businesses to keep gene-edited material out of certified supply chains, a concern it repeats in its assessment of what the Precision Breeding Act means for organic. Organic Farmers & Growers has made a similar case, warning that weaker coexistence and traceability provisions could disrupt non-GE and organic markets.

 

Updated: 11/05/2026

Regulations of gene editing and new breeding techniques (NBTs) worldwide are quickly evolving. Click on a country or region for more information on its regulatory status, what crops are approved or in development, and reactions from regional NGOs. The Gene Editing Index ratings represent their current status and will be updated as new regulations are approved.

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Agriculture Gene Editing Index
Compare Regulatory Restrictions Country-to-Country

Gene editing regulations worldwide are evolving. The Gene Editing Index ratings below represent the current status of gene editing regulations and will be updated as new regulations are passed.

Ratings Guide
 

Regulation StatusRating
Determined: No Unique Regulations*10
Lightly Regulated8
Proposed: No Unique Regulations†6
Ongoing Research, Regulations In Development5
Highly Regulated4
Mostly Prohibited2
Limited Research, No Clear Regulations1
Prohibited0
Lightly Regulated: Some or all types of gene editing are regulated more strictly than conventional agriculture, but not as strictly as transgenic GMOs.
*Determined: No Unique Regulations: Gene-edited crops that do not incorporate DNA from another species are regulated as conventional plants with no additional restrictions.

†Proposed: No Unique Regulations: Decrees under consideration for gene-edited crops that do not incorporate DNA from another species would no require unique regulations beyond current what is imposed on conventional breeding.

Crops/Food:
Gene editing of plants and food products. Research and development has mostly focused on disease resistance, drought resistance, and increasing yield, but more recent advances have produced low trans-fat oils and high-fiber grains.
Animals:
Gene editing of animals, not including animal research for human drugs and therapies. Fewer gene edited animals have been developed than gene edited crops, but scientists have developed hornless and heat-tolerant cattle and fast-growing tilapia may soon be the first gene edited animal to be consumed.

Rating by Country / Region
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Country / RegionFood / CropsAnimalsAg Rating
Ecuador101010
Norway666
Africa555
Japan888
Brazil101010
Canada888
Russia555
Argentina101010
Israel1057.5
Australia888
Switzerland555
China555
US1047
Chile1015.5
New Zealand444
Ukraine111
Central America666
Paraguay101010
Uruguay666
India666
UK222
Mexico111
EU222
Colombia1015.5
Country / RegionCrops / Food Rating
Australia^4
Canada*4
Chile^4
Costa Rica^4
Israel^4
Japan*4
Philippines*4
United States*4
Argentina^3
Bangladesh^3
Brazil*3
China*3
Colombia*3
Ecuador3
Ghana^3
Honduras3
India^3
Indonesia3
Kenya^3
Malawi^3
Nigeria^3
Pakistan3
Paraguay3
Uruguay3
Cuba^2
Guatamala2
El Salvador2
European Union^2
Norway2
South Africa^2
South Korea^2
Switzerland^2
United Kingdom^2
Bolivia1
Mexico1
New Zealand1
Peru1
Russia0

Approved Gene Edited / NBT Crops
Current list of foods developed by New Breeding Techniques that are approved for sale.

ProductDescriptionCountryCompany
Waxy cornCorn with high starch content developed using CRISPR.Approved:
Japan (2024)
Corteva Agriscience
Non-browning lettuceGreenVenus
Non-browning romaine lettuce.
Approved:
United States (2024)
Intrexon
Slick-coat cattlePRLR-SLICK cattle
Cows developed using CRISPR to grow short hair, which results in improved heat tolerance, which allows them to gain weight more easily.
Approved:
United States (2024)
Acceligen
Fungal resistant wheatEdit approved that confer resistance to a common fungal infection called powdery mildew that can be applied to different varieties.Approved:
China (2024)
Suzhou, Chinese Academy of Sciences
Mustard greensConscious Greens
Milder, less bitter mustard green developed using CRISPR-Cas12a.
Approved, available:
United States (2023)
Pairwise
Non-browning bananaBanana developed using CRISPR to slow the browning process for prolonged shelf-life.Approved:
Philippines (2023)
Tropic Biosciences
SeabreamRed Seabream
Fish developed using CRISPR disabling a gene suppressing muscle growth, allowing the fish to grow larger.
Approved, available:
Japan (2021)
Regional Fish Institute
GABA tomatoSicilian Rouge
Tomato edited using CRISPR to contain more GABA, a compound in tomato fruits and known to lower blood pressure.
Approved, available:
Japan (2021)
Sanantech Seed
Fast growing pufferfishTiger Pufferfish
Fish developed using CRISPR disrupting a gene controlling appetite, allowing the fish to eat more and grow faster.
Approved, available:
Japan (2021)
Regional Fish Institute
High-oleic soybean oilCalyno
Soybean oil with fewer saturated fats and zero trans fats, developed using a gene-editing technique called TALENs.
Approved, available: 
United States (2019)
Calyxt
Non-browning mushroomWhite Button Mushroom
Non-browning mushroom developed using a gene-editing technique called TALENs.
Approved:
United States (2016)
Pennsylvania State University
Non-browning appleArctic Apple
Non-browning apple (multiple varieties) developed with RNA interference, a more traditional New Breeding Technique (NBT). Varieties include Golden, Granny, Fuji, Gala, Honey.
Approved, available:
Canada (2017)
Approved, available:
United States (2015)
Okanagan Specialty Fruits
Non-browning potatoWhite Russet Potato
Non-browning, blight protection, lowered sugars, and low acrylamide potato developed with RNA interference.
Approved, available:
United States (2015)
Available:
Canada (2015)
Simplot
Rapeseed/CanolaDeveloped to be herbicide-tolerant canola using oligonnucleotide-direct mutagenesis (ODM).Approved:
United States (2014)
Canada (2013)
Cibus

Global gene editing regulatory landscape

The regulations on genetically engineered crops and animals are emerging out of the regulatory landscape developed for transgenic GMOs. Regulations across 34 countries where transgenic or gene edited crops and animals are commercially allowed (as of 12/19) are guided in part by two factors:
 
 
Whether the country has ratified the international agreement that took effect in 2003 that aims to ensure the safe handling, transport and use of living modified organisms (LMOs) resulting from biotechnology that may impact biological diversity, also taking into account potential risks to human health. It entered into force for those nations that signed it in 2003. It applies the ‘precautionary approach as contained in the Rio Declaration on Environment and Development. The US, Canada, Australia and Chile and the Russian Federation have not signed the treaty.
 
 
Whether regulations are based on the genetic process used to create the trait (conventional, mutagenesis, transgenesis, gene editing, etc.) or the final product.Transgenic crops and animals (aka GMOs) are product regulated in many countries including the US and Canada, while the EU, India, China and others regulate based on how the product is made. There is almost an equal number of countries with product- and process-based regulations. It’s not clear how much this distinction matters. It’s somewhat true that countries with product-based regulation have more crops approved and the approval process is more streamlined, but there are contradictions. For example, Brazil and Argentina have emerged as GMO super powers using different regulatory concepts, while there is no GMO commercial cultivation in Japan, North Korea, and the Russian Federation, which employ product-based regulations. How this will effect gene editing regulations is also unclear. For example, Japan, which has no commercialized GMOs, is emerging as a leader in the introduction of gene edited crops.
Agricultural Landscape

Gene editing is a set of techniques that can be used to precisely modify the DNA of almost any organism. It is being used for applications in human health, gene drives and agriculture. There are numerous gene-editing tools besides CRISPR-Cas 9, which gets most of the attention because it is a comparatively easy tool to use.

Gene editing does not usually involve transgenics – moving ‘foreign’ genes between species. It also refers to a specific technique in contrast to the general term GMO, which is scientifically ambiguous, as genetic modification is a process not a product. Most gene editing involves creating new products by deleting very small segments of DNA (sometimes in agriculture called Site-Directed Nuclease 1 or SDN-1 techniques), which can silence a gene or change a gene’s activity. Countries are evaluating whether or not to regulate this type of gene editing, since it is so similar to natural mutations. The GLP’s Gene Editing Index ratings reflect the regulatory status of SDN-1 techniques, which are the most liberally regulated and will generate most products in the near term.

To develop different products, gene editing can change larger segments of DNA or add DNA from other species (a form of transgenics sometimes in agriculture called SDN-2 or SDN-3 techniques). While many countries are not regulating or lightly regulating SDN-1 techniques, most are moving toward tightly regulating or even restricting SDN-2 and SDN-3.

For more background on the various gene editing SDN techniques, read background articles here and here.

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