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Mexico: Crops / Food

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Prohibited or restricted

Regulatory status of gene editing of crops has not been determined.

There are no approved gene edited crops or prospects for approval in the near future. Currently, they fall under highly restrictive laws established for transgenic GMOs, similar to the European Union and New Zealand. 

Mexico has not reported any biotechnology food or feed products approvals since May 2018. Herbicide-tolerant and insect-resistant cotton is the only GE crop currently planted in Mexico, and while production reached a record in 2018/2019, the lack of updated seed availability coupled with additional challenges in the sector reduced production since then by about 33 percent. Mexico has rejected or delayed all new permit applications for cultivation of genetically engineered cotton since 2019, citing the European-inspired precautionary principle. 

GE regulation responsibility falls under the authority of Mexico’s National Science and Technology Council (CONACYT). CONACYT manages the National Biosafety Registry (NBR), and authorizes the consumption of GE products, and it manages permitting the planting of GE seeds. In 2021 the NBR was updated by a presidential decree which called for the phase-out of the herbicide glyphosate and the importation of GE corn for both human and animal consumption for feed by January 2024. 

Also in 2021 Mexico’s health agency denied a permit for a new glyphosate-tolerant corn variety developed by Bayer/Monsanto. Around the same time, Mexico’s highest court upheld an injunction on the cultivation of genetically modified corn because it poses a credible threat to Mexico’s rich store of native corn biodiversity through uncontrolled cross-pollination. That injunction has been in place since 2013. The government has said that the GE corn would be replaced by sustainable and ‘culturally appropriate’ alternatives, although there is not enough domestic production to meet current demand, especially of feed corn. 

Mexico’s announced intention to ban GE crops is complicated by the United States-Mexico-Canada Agreement (USMCA) entered into force on July 1, 2020 after several years of negotiations. Covered products encompass products created with newer genome editing and other genetic engineering techniques, which are identified in the text as including modern biotechnology used for the deliberate manipulation of an organism to introduce, remove, or modify one or more heritable characteristics of a product for agriculture and aquaculture use and that are not technologies used in traditional breeding and selection.” 

The article defines “modern biotechnology” as “the application of: (a) in vitro nucleic acid techniques, including recombinant DNA and direct injection of nucleic acid into cells or organelles; or (b) fusion of cells beyond the taxonomic family, that overcome natural physiological reproductive or recombination barriers and that are not techniques used in traditional breeding and selection. The agreement does not require a party to mandate an authorization for a product of agricultural biotechnology to be on the market.

To succeed in an enforcement action against Mexico under this article, the U.S. would need to establish a specific obligation that Mexico failed to carry out or show that a benefit it could reasonably have expected to receive under the USMCA was “nullified or impaired” by Mexico’s actions. In December 2022, the Mexican government showed signs of backtracking on the ban decree to allow GE corn to be purchased for feed after backlash by the US government citing USMCA. No progress is being made on research or approvals of gene-edited products.

Products/Research

There are no gene edited crops in development.

Regulatory Timeline

2020: United States-Mexico-Canada Agreement (USMCA) entered into force on July 1, which has provisions on ‘Agricultural Biotechnology’.

2016: The Mexican state of Yucatan declares itself a “GMO” free zone, including all genetically engineered crops and products. The Decree was issued without the SAGARPA endorsement and is challenged by the Federal Government.

2013: Planting genetically modified maize in Mexico prohibited, pending the outcome of a lawsuit.

2012: SAGARPA and SEMARNAT publish the Agreement to Determine the Centers of Origin and Centers of Genetic Diversity of Corn in Mexico. This Agreement restricts the storage and movement of GE corn and includes a map delineating areas where the use of GE corn seed is forbidden.

2005: Mexican Biosafety Law is passed, which regulates the research, production, and marketing of biotech-derived products.

2002: Mexican Senate ratifies Cartagena Protocol on Biosafety (CPB), which obligates Mexico to pass domestic legislation harmonizing its domestic laws with international obligations. This led to the passing of the Mexican Biosafety Law in 2005.

NGO Reaction

NGOs are active detractors of biotechnology in Mexico. In addition, many consumers have concerns about the integrity of Mexico’s native corn species because corn is a symbol of heritage.

Additional Resources

Updated: 03/06/2023

Regulations of gene editing and new breeding techniques (NBTs) worldwide are quickly evolving. Click on a country or region for more information on its regulatory status, what crops are approved or in development, and reactions from regional NGOs. The Gene Editing Index ratings represent their current status and will be updated as new regulations are approved.

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Agriculture Gene Editing Index
Compare Regulatory Restrictions Country-to-Country

Gene editing regulations worldwide are evolving. The Gene Editing Index ratings below represent the current status of gene editing regulations and will be updated as new regulations are passed.

Ratings Guide
 

Regulation StatusRating
Determined: No Unique Regulations*10
Lightly Regulated8
Proposed: No Unique Regulations†6
Ongoing Research, Regulations In Development5
Highly Regulated4
Mostly Prohibited2
Limited Research, No Clear Regulations1
Prohibited0
Lightly Regulated: Some or all types of gene editing are regulated more strictly than conventional agriculture, but not as strictly as transgenic GMOs.
*Determined: No Unique Regulations: Gene-edited crops that do not incorporate DNA from another species are regulated as conventional plants with no additional restrictions.

†Proposed: No Unique Regulations: Decrees under consideration for gene-edited crops that do not incorporate DNA from another species would no require unique regulations beyond current what is imposed on conventional breeding.

Crops/Food:
Gene editing of plants and food products. Research and development has mostly focused on disease resistance, drought resistance, and increasing yield, but more recent advances have produced low trans-fat oils and high-fiber grains.
Animals:
Gene editing of animals, not including animal research for human drugs and therapies. Fewer gene edited animals have been developed than gene edited crops, but scientists have developed hornless and heat-tolerant cattle and fast-growing tilapia may soon be the first gene edited animal to be consumed.

Rating by Country / Region
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Country / RegionFood / CropsAnimalsAg Rating
Ecuador101010
Norway666
Africa555
Japan888
Brazil101010
Canada888
Russia555
Argentina101010
Israel1057.5
Australia888
Switzerland555
China555
US1047
Chile1015.5
New Zealand444
Ukraine111
Central America666
Paraguay101010
Uruguay666
India666
UK222
Mexico111
EU222
Colombia1015.5
Country / RegionCrops / Food Rating
Australia^4
Canada*4
Chile^4
Costa Rica^4
Israel^4
Japan*4
Philippines*4
United States*4
Argentina^3
Bangladesh^3
Brazil*3
China*3
Colombia*3
Ecuador3
Ghana^3
Honduras3
India^3
Indonesia3
Kenya^3
Malawi^3
Nigeria^3
Pakistan3
Paraguay3
Uruguay3
Cuba^2
Guatamala2
El Salvador2
European Union^2
Norway2
South Africa^2
South Korea^2
Switzerland^2
United Kingdom^2
Bolivia1
Mexico1
New Zealand1
Peru1
Russia0

Approved Gene Edited / NBT Crops
Current list of foods developed by New Breeding Techniques that are approved for sale.

ProductDescriptionCountryCompany
Waxy cornCorn with high starch content developed using CRISPR.Approved:
Japan (2024)
Corteva Agriscience
Non-browning lettuceGreenVenus
Non-browning romaine lettuce.
Approved:
United States (2024)
Intrexon
Slick-coat cattlePRLR-SLICK cattle
Cows developed using CRISPR to grow short hair, which results in improved heat tolerance, which allows them to gain weight more easily.
Approved:
United States (2024)
Acceligen
Fungal resistant wheatEdit approved that confer resistance to a common fungal infection called powdery mildew that can be applied to different varieties.Approved:
China (2024)
Suzhou, Chinese Academy of Sciences
Mustard greensConscious Greens
Milder, less bitter mustard green developed using CRISPR-Cas12a.
Approved, available:
United States (2023)
Pairwise
Non-browning bananaBanana developed using CRISPR to slow the browning process for prolonged shelf-life.Approved:
Philippines (2023)
Tropic Biosciences
SeabreamRed Seabream
Fish developed using CRISPR disabling a gene suppressing muscle growth, allowing the fish to grow larger.
Approved, available:
Japan (2021)
Regional Fish Institute
GABA tomatoSicilian Rouge
Tomato edited using CRISPR to contain more GABA, a compound in tomato fruits and known to lower blood pressure.
Approved, available:
Japan (2021)
Sanantech Seed
Fast growing pufferfishTiger Pufferfish
Fish developed using CRISPR disrupting a gene controlling appetite, allowing the fish to eat more and grow faster.
Approved, available:
Japan (2021)
Regional Fish Institute
High-oleic soybean oilCalyno
Soybean oil with fewer saturated fats and zero trans fats, developed using a gene-editing technique called TALENs.
Approved, available: 
United States (2019)
Calyxt
Non-browning mushroomWhite Button Mushroom
Non-browning mushroom developed using a gene-editing technique called TALENs.
Approved:
United States (2016)
Pennsylvania State University
Non-browning appleArctic Apple
Non-browning apple (multiple varieties) developed with RNA interference, a more traditional New Breeding Technique (NBT). Varieties include Golden, Granny, Fuji, Gala, Honey.
Approved, available:
Canada (2017)
Approved, available:
United States (2015)
Okanagan Specialty Fruits
Non-browning potatoWhite Russet Potato
Non-browning, blight protection, lowered sugars, and low acrylamide potato developed with RNA interference.
Approved, available:
United States (2015)
Available:
Canada (2015)
Simplot
Rapeseed/CanolaDeveloped to be herbicide-tolerant canola using oligonnucleotide-direct mutagenesis (ODM).Approved:
United States (2014)
Canada (2013)
Cibus

Global gene editing regulatory landscape

The regulations on genetically engineered crops and animals are emerging out of the regulatory landscape developed for transgenic GMOs. Regulations across 34 countries where transgenic or gene edited crops and animals are commercially allowed (as of 12/19) are guided in part by two factors:
 
 
Whether the country has ratified the international agreement that took effect in 2003 that aims to ensure the safe handling, transport and use of living modified organisms (LMOs) resulting from biotechnology that may impact biological diversity, also taking into account potential risks to human health. It entered into force for those nations that signed it in 2003. It applies the ‘precautionary approach as contained in the Rio Declaration on Environment and Development. The US, Canada, Australia and Chile and the Russian Federation have not signed the treaty.
 
 
Whether regulations are based on the genetic process used to create the trait (conventional, mutagenesis, transgenesis, gene editing, etc.) or the final product.Transgenic crops and animals (aka GMOs) are product regulated in many countries including the US and Canada, while the EU, India, China and others regulate based on how the product is made. There is almost an equal number of countries with product- and process-based regulations. It’s not clear how much this distinction matters. It’s somewhat true that countries with product-based regulation have more crops approved and the approval process is more streamlined, but there are contradictions. For example, Brazil and Argentina have emerged as GMO super powers using different regulatory concepts, while there is no GMO commercial cultivation in Japan, North Korea, and the Russian Federation, which employ product-based regulations. How this will effect gene editing regulations is also unclear. For example, Japan, which has no commercialized GMOs, is emerging as a leader in the introduction of gene edited crops.
Agricultural Landscape

Gene editing is a set of techniques that can be used to precisely modify the DNA of almost any organism. It is being used for applications in human health, gene drives and agriculture. There are numerous gene-editing tools besides CRISPR-Cas 9, which gets most of the attention because it is a comparatively easy tool to use.

Gene editing does not usually involve transgenics – moving ‘foreign’ genes between species. It also refers to a specific technique in contrast to the general term GMO, which is scientifically ambiguous, as genetic modification is a process not a product. Most gene editing involves creating new products by deleting very small segments of DNA (sometimes in agriculture called Site-Directed Nuclease 1 or SDN-1 techniques), which can silence a gene or change a gene’s activity. Countries are evaluating whether or not to regulate this type of gene editing, since it is so similar to natural mutations. The GLP’s Gene Editing Index ratings reflect the regulatory status of SDN-1 techniques, which are the most liberally regulated and will generate most products in the near term.

To develop different products, gene editing can change larger segments of DNA or add DNA from other species (a form of transgenics sometimes in agriculture called SDN-2 or SDN-3 techniques). While many countries are not regulating or lightly regulating SDN-1 techniques, most are moving toward tightly regulating or even restricting SDN-2 and SDN-3.

For more background on the various gene editing SDN techniques, read background articles here and here.

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